Repeatability and Reproducibility of Microdosimetry With a Mini-TEPC

Experimental microdosimetry measures the energy deposited in a microscopic sensitive volume ( SV ) by single ionizing particles traversing or passing by. The fundamental advantage of experimental over computational approach is that first allows to determine distributions deposition when information on and nature charged at point interest incomplete fragmentary. This almost always case radiation protection applications, but discrepancies between modelled actual scenarios should be considered also therapy. Models for physical reality are imperfect rely both basic input data assumptions simplifications necessarily implemented. Furthermore, unintended events due human errors machine/system failures can minimized cannot completely avoided. Though proton therapy (PRT) constant relative biological effectiveness (RBE) 1.1 assumed, there evidence an increasing RBE towards end penetration depth. Treatment Planning Systems (TPS) take into account variable linear transfer (LET) already available could implemented PRT near future. However, while calculated dose produced TPS routinely verified with ionization chambers as part quality assurance program every radiotherapy center, no commercial detector currently perform routine verification quality, through LET distributions. Verification required make sure complex robustly optimized plan will delivered planned. scientific community coming conclusion new domain Quality Assurance additionally required, right address that. A important prerequisite repeatability reproducibility microdosimetric measurements. work aims studying experimentally measurements performed miniaturized Tissue Equivalent Proportional Counter (mini-TEPC) 62 MeV beam. Experiments were carried out within 1 year without propane gas recharging different operators. was applying Loncol’s weighting function r(y) Demonstration measured quantities y¯F , id="m2">y¯D 10 beam makes this TEPC possible metrological tool Future characterization higher beams.